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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $451 | In Stock | |
200 μg | $797 | 7-10 days | |
500 μg | $1,680 | 7-10 days |
Biological Information | Testing in progress |
Description | Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641. |
Species | Human |
Expression System | HEK293 Cells |
Tag | C-His |
Accession Number | Q13641 |
Synonyms | 5T4AG,trophoblast glycoprotein,WAIF1,M6P1,5T4 |
Construction | The Human TPBG (NP_006661.1) (Asp60-Asp345) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity | ≥ 95 % as determined by SDS-PAGE. ≥90 % as determined by SEC-HPLC. |
Molecular Weight | 33.1 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. |
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