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BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

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BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

Catalog No. TMPY-00680

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060.

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Pack Size	Price	Availability	Quantity
20 μg	$136	In Stock
100 μg	$346	In Stock

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Biological Description

Biological Information	Testing in progress
Description	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060.
Species	Human,Mouse,Rat,Rhesus,Canine
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	C8C060
Synonyms	bone morphogenetic protein 2
Construction	The mature form of Human / Mouse / Rat / rhesus / canine BMP2 (NP_001191.1) (Gln 283-Arg 396) was fused with the Fc region of Human IgG1 at the N-terminus. The mature form sequences of Human, Mouse, Rat, rhesus and canine BMP2 are identical.
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	39.5 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.