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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 μg | $310 | Backorder | |
50 μg | $1,165 | Backorder | |
500 μg | $5,832 | Backorder |
Description | Recombinant Human Bone morphogenetic protein 7 is produced by our Mammalian expression system and the target gene encoding Ser293-His431 is expressed. |
Species | Human |
Expression System | HEK293 Cells |
Tag | Tag Free |
Accession Number | P18075 |
Synonyms | Eptotermin alfa,OP-1,OP1,Osteogenic protein 1,Bone morphogenetic protein 7,BMP7 |
Amino Acid | Ser293-His431 |
Construction | Ser293-His431 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Molecular Weight | 18-23 KDa (reducing condition) |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as a 0.2 μm filtered solution of 20 mM PB, 100 mM NaCl, 5% Mannitol, 0.05% Tween 80, pH7.5. |
Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 6 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a state of leptin-resistance, thus a protein-like BMP7 which acts through a leptin-independent pathway could give new therapeutic directions. |
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