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Claudin-18 Protein-VLP, Mouse, Recombinant (His)
Catalog No. TMPH-02586
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-18 Protein-VLP, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 29.1 kDa and the accession number is P56857.
Claudin-18 Protein-VLP, Mouse, Recombinant (His)
Catalog No. TMPH-02586
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-18 Protein-VLP, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 29.1 kDa and the accession number is P56857.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μg | $776 | 20 days | |
| 100 μg | $1,700 | 20 days | |
| 1 mg | $9,640 | 20 days |
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Product Information
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized Mouse Cldn18 at 5 μg/mL can bind Anti-CLDN18.2 recombinant antibody, the EC 50 is 6.115-11.01 ng/mL. |
| Description | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-18 Protein-VLP, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 29.1 kDa and the accession number is P56857. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | N-6xHis (This tag can be tested only under denaturing conditions) |
| Accession Number | P56857 |
| Synonyms | CLDN18,Claudin 18 |
| Amino Acid | MSVTACQGLGFVVSLIGFAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVSYHASGQNVAYRPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPTKYDYV |
| Construction | 1-264 aa |
| Molecular Weight | 29.1 kDa (predicted) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 6% Trehalose, pH 7.4 |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
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