Claudin-6 Protein-VLP, Cynomolgus, Recombinant

Catalog No. TMPK-00667

Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.60 kDa and the accession number is G7Q0B0.

Claudin-6 Protein-VLP, Cynomolgus, Recombinant

Catalog No. TMPK-00667

Pack Size	Price	Availability
100 μg	$1,620	7-10 days
500 μg	$6,520	7-10 days
1 mg	$10,870	7-10 days

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Product Information

Biological Activity	1. Immobilized Cynomolgus Claudin 6 VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 4ng/ml determined by ELISA (QC Test). 2. Cynomolgus Claudin 6 VLP immobilized on CM5 Chip can bind Anti-Claudin 6 Antibody with an affinity constant of 0.85 nM as determined in SPR assay.
Description	Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.60 kDa and the accession number is G7Q0B0.
Species	Cynomolgus
Expression System	HEK293 Cells
Accession Number	G7Q0B0
Synonyms	Skullin 2,Skullin,EGM_11390,CLDN6,Claudin-6,Claudin6,Claudin
Construction	Met1-Val220
Protein Purity	> 95% as determined by HPLC
Molecular Weight	24.60 kDa (predicted)
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.