Claudin-6 Protein-VLP, Human, Recombinant

Catalog No. TMPK-00904

Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.5 kDa and the accession number is P56747.

Claudin-6 Protein-VLP, Human, Recombinant

Catalog No. TMPK-00904

Pack Size	Price	Availability
100 μg	$1,620	7-10 days
500 μg	$6,520	7-10 days
1 mg	$10,870	7-10 days

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Product Information

Biological Activity	1. Immobilized Human Claudin 6 VLP at 5μg/ml (100μl/Well). Dose response curve for Anti-Claudin 6 Antibody, mFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). 2. Human Claudin 6 VLP immobilized on CM5 Chip can bind Anti-Claudin 6 Antibody with an affinity constant of 0.36 nM as determined in SPR assay.
Description	Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.5 kDa and the accession number is P56747.
Species	Human
Expression System	HEK293 Cells
Accession Number	P56747
Synonyms	Skullin 2,Skullin,CLDN6,Claudin-6,Claudin6
Construction	Met1-Val220
Protein Purity	> 95% as determined by HPLC.
Molecular Weight	24.5 kDa (predicted)
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.