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CXCL7 Protein, Cynomolgus, Rhesus, Recombinant (His)

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CXCL7 Protein, Cynomolgus, Rhesus, Recombinant (His)

Catalog No. TMPY-04725

CXCL7 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 11.7 kDa and the accession number is A0A2K5UVV0.

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Pack Size	Price	Availability	Quantity
100 μg	$618	7-10 days

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Biological Description

Biological Information	Testing in progress
Description	CXCL7 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 11.7 kDa and the accession number is A0A2K5UVV0.
Species	Cynomolgus,Rhesus
Expression System	P. pastoris (Yeast)
Tag	C-His
Accession Number	A0A2K5UVV0
Synonyms	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
Construction	The cynomolgus / rhesus CXCL7 (XP_005555138.1) (Ser35-Asp128) was expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus CXCL7 sequences are identical.
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	11.7 kDa (predicted)
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 30% CAN, 0.1% TFA. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2 / PPBP / CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy