FGF-9 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-00804

FGF-9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54 and 37 kDa and the accession number is A0A7U3L6D0.

FGF-9 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-00804

FGF-9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54 and 37 kDa and the accession number is A0A7U3L6D0.

Pack Size	Price	Availability
20 μg	$136	In Stock
100 μg	$320	7-10 days
200 μg	$553	7-10 days

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Product Information

Biological Activity	Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 10-60 ng/mL.
Description	FGF-9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54 and 37 kDa and the accession number is A0A7U3L6D0.
Species	Human
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	P31371
Synonyms	SYNS3,HBGF-9,HBFG-9,GAF,fibroblast growth factor 9,FGF-9
Construction	A DNA sequence encoding the mature form of human fibroblast growth factor 9 (NP_002001.1) (Leu 4-Ser 208) was expressed with the fused Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu 20
Protein Purity	> 85 %, as determined by SDS-PAGE
Molecular Weight	54 and 37 kDa (predicted); 54 and 37 kDa (reducing condition, due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor or Heparin-binding growth factor 9, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. FGF9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF9 may have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.