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Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed. GPC3 Protein-VLP, Human, Recombinant (aa 438-554) is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.5 kDa and the accession number is P51654-1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $1,850 | 7-10 days | |
500 μg | $7,460 | 7-10 days | |
1 mg | $12,430 | 7-10 days |
Biological Activity | Immobilized Human GPC3 (438-554) VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-GPC3 Antibody, hFc Tag with the EC50 of 24.1ng/ml determined by ELISA. |
Description | Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed. GPC3 Protein-VLP, Human, Recombinant (aa 438-554) is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.5 kDa and the accession number is P51654-1. |
Species | Human |
Expression System | HEK293 Cells |
Accession Number | P51654-1 |
Synonyms | SGBS1SDYS,SGBS1,SGBS,SGB,SDYS,OCI-5,OCI5,MXR7,GTR2-2,GPC3,Glypican 3,DGSX |
Construction | Arg438-Asn554 |
Protein Purity | ; > 95% as determined by HPLC |
Molecular Weight | 21.5 kDa (predicted) |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant. |
Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | Shipping with blue ice. |
Research Background | Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed. |
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