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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μg | $383 | 7-10 days | |
1 mg | $3,910 | 7-10 days |
Biological Information | Testing in progress |
Description | GRO gama/CXCL3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P19876. |
Species | Human |
Expression System | E. coli |
Tag | N-His |
Accession Number | P19876 |
Synonyms | MIP-2b,MIP2B,CXCL3,SCYB3,GRO γ,CINC-2b,chemokine (C-X-C motif) ligand 3,GROG,GRO3 |
Construction | Human CXCL3 (NP_002081.2) (Ala35-Asn107) |
Protein Purity | > 90 % as determined by SDS-PAGE |
Molecular Weight | 10.1 kDa (predicted) |
Endotoxin | Please contact us for more information. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | CXCL3 is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3 autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. CXCL3 and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis. |
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