IL-13RA1 Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPY-04816

IL-13RA1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is A0A7N9D0M5.

IL-13RA1 Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPY-04816

IL-13RA1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is A0A7N9D0M5.

Pack Size	Price	Availability	Quantity
100 μg	$600	7-10 days
1 mg	$3,910	7-10 days

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Product Information

Biological Activity	Immobilized Recombinant Human IL13 Protein (Fc Tag) at 2μg/mL (100μL/well) can bind Recombinant Cynomolgus IL13RA1 / IL-13RA1 Protein (His Tag), the EC50 is 90-380 ng/mL.
Description	IL-13RA1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is A0A7N9D0M5.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	A0A7N9D0M5
Synonyms	interleukin 13 receptor, α1,interleukin 13 receptor, alpha 1
Construction	A DNA sequence encoding the cynomolgus IL13RA1 (XP_005594500.1) (Met1-Thr341) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 25
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	37.9 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.