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INSL4 Protein, Human, Recombinant (His)
Catalog No. TMPY-00471
INSL4 (Insulin-Like 4) is a Protein Coding gene. An important paralog of this gene is RLN1. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains or just the A and B chains. INSL4 is a member of the insulin family, which includes insulin, IGF-I, IGF-II, relaxin, and INSL3.INSL4 distribution was tissue- and cell-specific. Indeed, INSL4 mRNA was most abundant in syncytiotrophoblast cells. In fetal tissues, INSL4 mRNA was identified in the perichondrium of all four limbs, vertebrae, and ribs. Diseases associated with INSL4 include Placenta Accreta and Chromosome 9P Deletion Syndrome.
INSL4 Protein, Human, Recombinant (His)
Catalog No. TMPY-00471
INSL4 (Insulin-Like 4) is a Protein Coding gene. An important paralog of this gene is RLN1. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains or just the A and B chains. INSL4 is a member of the insulin family, which includes insulin, IGF-I, IGF-II, relaxin, and INSL3.INSL4 distribution was tissue- and cell-specific. Indeed, INSL4 mRNA was most abundant in syncytiotrophoblast cells. In fetal tissues, INSL4 mRNA was identified in the perichondrium of all four limbs, vertebrae, and ribs. Diseases associated with INSL4 include Placenta Accreta and Chromosome 9P Deletion Syndrome.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $700 | 7-10 days |
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| Biological Activity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | INSL4 (Insulin-Like 4) is a Protein Coding gene. An important paralog of this gene is RLN1. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains or just the A and B chains. INSL4 is a member of the insulin family, which includes insulin, IGF-I, IGF-II, relaxin, and INSL3.INSL4 distribution was tissue- and cell-specific. Indeed, INSL4 mRNA was most abundant in syncytiotrophoblast cells. In fetal tissues, INSL4 mRNA was identified in the perichondrium of all four limbs, vertebrae, and ribs. Diseases associated with INSL4 include Placenta Accreta and Chromosome 9P Deletion Syndrome. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q14641 |
| Synonyms | PLACENTIN,insulin-like 4 (placenta),EPIL |
| Construction | A DNA sequence encoding the human INSL4 (Q14641)(Met1-Thr139) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Ala 26 |
| Protein Purity | > 95 % as determined by SDS-PAGE |
| Molecular Weight | 14 kDa (predicted); 12 kDa (reducing conditions) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. |
| Research Background | INSL4 (Insulin-Like 4) is a Protein Coding gene. An important paralog of this gene is RLN1. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains or just the A and B chains. INSL4 is a member of the insulin family, which includes insulin, IGF-I, IGF-II, relaxin, and INSL3.INSL4 distribution was tissue- and cell-specific. Indeed, INSL4 mRNA was most abundant in syncytiotrophoblast cells. In fetal tissues, INSL4 mRNA was identified in the perichondrium of all four limbs, vertebrae, and ribs. Diseases associated with INSL4 include Placenta Accreta and Chromosome 9P Deletion Syndrome. |
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