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MASP2 Protein, Mouse, Recombinant (His)

Catalog No. TMPK-01126

MASP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q91WP0.

MASP2 Protein, Mouse, Recombinant (His)

MASP2 Protein, Mouse, Recombinant (His)

Catalog No. TMPK-01126
MASP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q91WP0.
Pack SizePriceAvailabilityQuantity
100 μg$6277-10 days
500 μg$2,5107-10 days
1 mg$4,2007-10 days
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Product Information

Biological Activity
Immobilized Mouse MASP2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-MASP2 Antibody, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA.
Description
MASP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q91WP0.
Species
Mouse
Expression System
E. coli
TagC-His
Accession NumberQ91WP0
Synonyms
sMap,MASP-2,MASP1P1,MAP19
Construction
Thr287-Phe685
Protein Purity
> 95% as determined by Tris-Bis PAGE
Molecular Weight46.6 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.
Endotoxin< 1 EU/μg by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 50 mM Tris, 200 mM NaCl (pH 9.0).
Stability & Storage
It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingShipping with blue ice.
Research Background
The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.

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