MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated

Catalog No. TMPK-00582

MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.

MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated

Catalog No. TMPK-00582

Pack Size	Price	Availability
100 μg	$932	7-10 days
500 μg	$3,720	7-10 days
1 mg	$6,210	7-10 days

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Product Information

Biological Activity	Immobilized Anti-MASP2 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Rat MASP2, His Tag with the EC50 of 19.3ng/ml determined by ELISA.
Description	MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
Species	Rat
Expression System	E. coli
Tag	C-His
Accession Number	A2VCV7
Synonyms	sMap,MASP-2,MASP1P1,MAP19
Construction	Thr287-Phe685
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 50 mM Tris, 200 mM NaCl (pH 9.0).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.