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MCP-1/CCL2 Protein, Human, Recombinant (His)

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COA

MCP-1/CCL2 Protein, Human, Recombinant (His)

Catalog No. TMPY-00118

MCP-1/CCL2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P13500.

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Pack Size	Price	Availability
50 μg	$245	In Stock
100 μg	$413	7-10 days
200 μg	$693	7-10 days
500 μg	$2,130	7-10 days

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Biological Description

Biological Information	Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with mouse CCR2. The ED50 for this effect is 20-200 ng/mL.
Description	MCP-1/CCL2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P13500.
Species	Human
Expression System	P. pastoris (Yeast)
Tag	C-His
Accession Number	P13500
Synonyms	SCYA2,HC11,MCAF,HSMCR30,MCP-1,MCP1,GDCF-2,SMC-CF,chemokine (C-C motif) ligand 2
Construction	The Human CCL2 (NP_002973.1) (Gln24-Thr99) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	10.1 kDa (predicted)
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy