Testing in progress

MIP-1 alpha/CCL3 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.2 kDa and the accession number is A0N0R1.

Human

P. pastoris (Yeast)

LD78α,chemokine (C-C motif) ligand 3,MIP-1-alpha,G0S19-1,MIP-1-α,SCYA3,MIP1A,LD78ALPHA,MIP-1 α

Human CCL3 (NP_002974.1) (Ala23-Ala92) was expressed with a polyhistidine tag at the C-terminus.

> 95 % as determined by SDS-PAGE

A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CCL3 is a cytokine belonging to the CC chemokine family. Chemokines are a family of structurally related leukocyte chemoattractant cytokines that play a central role during immunoregulatory and inflammation processes. All chemokines contain four conserved cysteines linked by disulfide bonds, and two major subfamilies, namely CXC and CC, are defined on the basis of the first two cysteines which are separated by one amino acid or are adjacent. CCL3 is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy