Shopping Cart

Remove All

Your shopping cart is currently empty

Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)

Resource Download

Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)

Catalog No. TMPY-04237

Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.7 kDa.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability	Quantity
100 μg	$306	7-10 days

Bulk & Custom

Add to Cart

Questions

Biological Description

Biological Information	Testing in progress
Description	Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.7 kDa.
Species	Canine
Expression System	HEK293 Cells
Tag	N-His
Synonyms	neuregulin 1
Construction	canine NRG1 (Ser176-Lys240)
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	9.7 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis.