NTNG1 Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-01401

Netrin-G1, known as NTNG-1, and is a member of the UNC-6/Netrin family of proteins. The NTNG1 gene is located on chromosome 1p13.3 and encodes a glycosylphosphatidylinositol protein anchored to the presynaptic membrane. Netrin G1 molecule has been described to be involved in axonal guidance/maintenance and axonal growth cone by specifically interacting with its receptor the Netrin G1 ligand (NGL-1), which is located at the postsynaptic compartment. Netrin Gs knockout mice have disturbed subdendritic laminar organization of their specific synaptic ligands (Ngl1 and Ngl2).

NTNG1 Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-01401

Pack Size	Price	Availability
10 μg	$123	7-10 days
50 μg	$371	7-10 days
500 μg	$2,230	7-10 days
1 mg	$3,350	7-10 days

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Product Information

Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Netrin-G1, known as NTNG-1, and is a member of the UNC-6/Netrin family of proteins. The NTNG1 gene is located on chromosome 1p13.3 and encodes a glycosylphosphatidylinositol protein anchored to the presynaptic membrane. Netrin G1 molecule has been described to be involved in axonal guidance/maintenance and axonal growth cone by specifically interacting with its receptor the Netrin G1 ligand (NGL-1), which is located at the postsynaptic compartment. Netrin Gs knockout mice have disturbed subdendritic laminar organization of their specific synaptic ligands (Ngl1 and Ngl2).
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q9Y2I2
Synonyms	NTNG1,Netrin-G1,LMNT1,Laminet-1
Amino Acid	His29-Ser409
Construction	His29-Ser409
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	80-90 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Netrin-G1, known as NTNG-1, and is a member of the UNC-6/Netrin family of proteins. The NTNG1 gene is located on chromosome 1p13.3 and encodes a glycosylphosphatidylinositol protein anchored to the presynaptic membrane. Netrin G1 molecule has been described to be involved in axonal guidance/maintenance and axonal growth cone by specifically interacting with its receptor the Netrin G1 ligand (NGL-1), which is located at the postsynaptic compartment. Netrin Gs knockout mice have disturbed subdendritic laminar organization of their specific synaptic ligands (Ngl1 and Ngl2).