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SARS-CoV-2 NSP10 Protein (His)

SARS-CoV-2 NSP10 Protein (His)
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SARS-CoV-2 NSP10 Protein (His)

Catalog No. TMPY-06011
NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp14 and nsp16 and possibly other subunits of the viral replication complex may be a target for the development of antiviral compounds against pathogenic coronaviruses. SARS-CoV-2 NSP10 Protein (His) is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is YP_009725306.1.
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Pack SizePriceAvailabilityQuantity
100 μg$6987-10 days
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Biological Description

Biological Information
Testing in progress
Description
NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp14 and nsp16 and possibly other subunits of the viral replication complex may be a target for the development of antiviral compounds against pathogenic coronaviruses. SARS-CoV-2 NSP10 Protein (His) is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is YP_009725306.1.
Species
SARS-CoV-2
Expression System
E. coli
TagC-His
Accession NumberYP_009725306.1
Construction
The SARS-CoV-2 (2019-nCoV) NSP10 (YP_009725306.1) (Ala1-Gln139) was expressed with an initial Met at the N-terminus and a polyhistidine tag at the C-terminus.
Protein Purity
> 95 % as determined by SDS-PAGE.
Molecular Weight15.7 kDa (predicted)
EndotoxinPlease contact us for more information.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp14 and nsp16 and possibly other subunits of the viral replication complex may be a target for the development of antiviral compounds against pathogenic coronaviruses.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.