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TARC Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 8.2 kDa and the accession number is Q9WUZ6.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μg | 395 € | 7-10 days | |
1 mg | 3.625 € | 7-10 days |
Biological Activity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
Description | TARC Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 8.2 kDa and the accession number is Q9WUZ6. |
Species | Mouse |
Expression System | Baculovirus Insect Cells |
Tag | Tag Free |
Accession Number | Q9WUZ6 |
Synonyms | Tarc,Scya17l,Scya17,chemokine (C-C motif) ligand 17,Abcd-2 |
Construction | A DNA sequence encoding the mouse CCL17 (AAD56601.1) (Met 1-Pro 93) was expressed and purified. Predicted N terminal: Ala 21 |
Protein Purity | > 98 % as determined by SDS-PAGE |
Molecular Weight | 8.2 kDa (predicted); 8.2 kDa (reducing conditions) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4. |
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