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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $487 | 7-10 days | |
500 μg | $1,950 | 7-10 days | |
1 mg | $3,250 | 7-10 days |
Description | TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis. |
Species | Cynomolgus |
Expression System | E. coli |
Tag | N-His |
Accession Number | XP_005590891.2 |
Synonyms | Tryptase alpha/beta-1,TPSB1,Tryptase I,TPS2,TPS1,Tryptase alpha-1,Tryptase-1,Tryptase α/β-1,Tryptase α-1 |
Construction | Ile38-Pro282 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | 28.57kDa (predicted). The protein migrates to 30-33kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 250 mM NaCl, 2 mM CaCl2, 10% Glycerol (pH 8.0). |
Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis. |
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