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TPSAB1 protein, Cynomolgus, Recombinant (His)

TPSAB1 protein, Cynomolgus, Recombinant (His)
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TPSAB1 protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-01303
TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsin­like activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.
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Pack SizePriceAvailabilityQuantity
100 μg$4877-10 days
500 μg$1,9507-10 days
1 mg$3,2507-10 days
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Biological Description

Description
TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsin­like activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.
Species
Cynomolgus
Expression System
E. coli
TagN-His
Accession NumberXP_005590891.2
Synonyms
Tryptase alpha/beta-1,TPSB1,Tryptase I,TPS2,TPS1,Tryptase alpha-1,Tryptase-1,Tryptase α/β-1,Tryptase α-1
Construction
Ile38-Pro282
Protein Purity
> 95% as determined by Tris-Bis PAGE
Molecular Weight28.57kDa (predicted). The protein migrates to 30-33kDa based on Tris-Bis PAGE result.
Endotoxin< 1 EU/μg by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 20 mM Tris, 250 mM NaCl, 2 mM CaCl2, 10% Glycerol (pH 8.0).
Stability & Storage
It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsin­like activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.

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