TPSAB1 protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-01303

TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.

TPSAB1 protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-01303

Pack Size	Price	Availability
100 μg	$487	7-10 days
500 μg	$1,950	7-10 days
1 mg	$3,250	7-10 days

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User Guide of Recombinant Proteins

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Product Information

Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.
Species	Cynomolgus
Expression System	E. coli
Tag	N-His
Accession Number	XP_005590891.2
Synonyms	Tryptase-1,Tryptase α-1,Tryptase α/β-1,Tryptase I,Tryptase alpha-1,Tryptase alpha/beta-1,TPSB1,TPS2,TPS1
Construction	Ile38-Pro282
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	28.57kDa (predicted). The protein migrates to 30-33kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 20 mM Tris, 250 mM NaCl, 2 mM CaCl2, 10% Glycerol (pH 8.0).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	TPSAB1, namely tryptase alpha/beta-1, is a serine protease with trypsinlike activity. TPSAB1 is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. It may play a role in innate immunity. Diseases associated with TPSAB1 include mastocytosis and systemic mastocytosis.