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(±)15-HETE

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Catalog No. T18649Cas No. 71030-36-9

(±)15-HETE is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(±)15-HETE
Other Forms of (±)15-HETE:
15(R)-HETET84605
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(±)15-HETE

😃Good
Catalog No. T18649Cas No. 71030-36-9
(±)15-HETE is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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25 μg$23935 days
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Product Introduction

Bioactivity
Description
(±)15-HETE is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
In vitro
PROTACs consist of two ligands linked together: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. By leveraging the ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1].
Chemical Properties
Molecular Weight320.47
FormulaC20H32O3
Cas No.71030-36-9
Relative Density.0.984 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

(±)15 HETE15-HETE(±)15HETE
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