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(1S,4R)-N-Desmethyl Sertraline Hydrochloride

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

Catalog No. T9395Cas No. 675126-07-5

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Purity:99.71%

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(1S,4R)-N-Desmethyl Sertraline Hydrochloride

Catalog No. T9395Cas No. 675126-07-5

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$118	In Stock
5 mg	$280	In Stock
10 mg	$410	In Stock
25 mg	$642	In Stock
50 mg	$870	In Stock
100 mg	$1,170	In Stock
200 mg	$1,570	In Stock
1 mL x 10 mM (in DMSO)	$275	In Stock

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Product Introduction

Bioactivity

Description

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

Chemical Properties

Molecular Weight	328.66
Formula	C₁₆H₁₆Cl₃N
Cas No.	675126-07-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 60 mg/mL (182.56 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0427 mL	15.2133 mL	30.4266 mL	152.1329 mL
5 mM	0.6085 mL	3.0427 mL	6.0853 mL	30.4266 mL
10 mM	0.3043 mL	1.5213 mL	3.0427 mL	15.2133 mL
20 mM	0.1521 mL	0.7607 mL	1.5213 mL	7.6066 mL
50 mM	0.0609 mL	0.3043 mL	0.6085 mL	3.0427 mL
100 mM	0.0304 mL	0.1521 mL	0.3043 mL	1.5213 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

(1S,4R) N Desmethyl Sertraline Hydrochloride(1S,4R)NDesmethyl Sertraline HydrochlorideN-Desmethyl Sertraline Hydrochloride

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