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(E)-LHF-535

Name: (E)-LHF-535
Brand: TargetMol
SKU: T11138
Price: 39 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T11138Cas No. 2449213-57-2

(E)-LHF-535, the E-isomer of LHF-535, is an antiviral agent with EC50 values of <1 μM for Lassa, Machupo, and Junin viruses, and 1-10 μM for VSVg virus [1].

(E)-LHF-535

😃Good

Catalog No. T11138Cas No. 2449213-57-2

(E)-LHF-535, the E-isomer of LHF-535, is an antiviral agent with EC50 values of <1 μM for Lassa, Machupo, and Junin viruses, and 1-10 μM for VSVg virus [1].

Pack Size	Price	Availability
25 mg	$987	10-14 weeks
50 mg	$1,360	10-14 weeks
100 mg	$1,996	10-14 weeks

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Product Introduction

Bioactivity

Description

(E)-LHF-535, the E-isomer of LHF-535, is an antiviral agent with EC50 values of <1 μM for Lassa, Machupo, and Junin viruses, and 1-10 μM for VSVg virus [1].

Chemical Properties

Molecular Weight	412.52
Formula	C₂₇H₂₈N₂O₂
Cas No.	2449213-57-2
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 60 mg/mL (145.45 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4241 mL	12.1206 mL	24.2412 mL	121.2062 mL
5 mM	0.4848 mL	2.4241 mL	4.8482 mL	24.2412 mL
10 mM	0.2424 mL	1.2121 mL	2.4241 mL	12.1206 mL
20 mM	0.1212 mL	0.6060 mL	1.2121 mL	6.0603 mL
50 mM	0.0485 mL	0.2424 mL	0.4848 mL	2.4241 mL
100 mM	0.0242 mL	0.1212 mL	0.2424 mL	1.2121 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

(E) LHF 535LHF 535(E)LHF535LHF535LHF-535