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(E/Z)-BIO-acetoxime

Catalog No. T61890Cas No. 740841-15-0

(E/Z) - BIO-acetoxime is effective and selective GSK-3 α/β Inhibitors. For GSK-3 α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, IC50 are 10nM, 2.4 μM, 4.3 μ M, 63 μ M, respectively。

(E/Z)-BIO-acetoxime
Other Forms of (E/Z)-BIO-acetoxime:
BIO-acetoximeT6787667463-85-6
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(E/Z)-BIO-acetoxime

Catalog No. T61890Cas No. 740841-15-0
(E/Z) - BIO-acetoxime is effective and selective GSK-3 α/β Inhibitors. For GSK-3 α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, IC50 are 10nM, 2.4 μM, 4.3 μ M, 63 μ M, respectively。
Pack SizePriceAvailabilityQuantity
1 mg$7835 days
10 mg$59535 days
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Product Introduction

Bioactivity
Description
(E/Z) - BIO-acetoxime is effective and selective GSK-3 α/β Inhibitors. For GSK-3 α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B, IC50 are 10nM, 2.4 μM, 4.3 μ M, 63 μ M, respectively。
In vitro
(E/Z)-BIO-acetoxime (compound 13) demonstrates a selectivity greater than 200-fold for GSK-3α/β over CDK5/p25, CDK2/cyclin A, and CDK1/cyclin B, exhibiting IC50 values of 0.01, 2.4, 4.3, and 63 μM, respectively [1].
Chemical Properties
Molecular Weight398.21
FormulaC18H12BrN3O3
Cas No.740841-15-0
Storage & Solubility Information
StorageShipping with blue ice.

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