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(R)-PS210

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Catalog No. T12639Cas No. 1410101-89-1

(R)-PS210, the R enantiomer of PS210, is a substrate-selective allosteric PDK1 activator with an (AC50 of 1.8 μM).

(R)-PS210
Other Forms of (R)-PS210:
PS210T166701221962-86-2
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(R)-PS210

😃Good
Catalog No. T12639Cas No. 1410101-89-1
(R)-PS210, the R enantiomer of PS210, is a substrate-selective allosteric PDK1 activator with an (AC50 of 1.8 μM).
Pack SizePriceAvailabilityQuantity
25 mg$7666-8 weeks
50 mg$9956-8 weeks
100 mg$1,6106-8 weeks
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Product Introduction

Bioactivity
Description
(R)-PS210, the R enantiomer of PS210, is a substrate-selective allosteric PDK1 activator with an (AC50 of 1.8 μM).
Targets&IC50
PDK1:1.8 μM
In vitro
(R)-PS210 displays an AC50 value of 1.8 μM towards PDK1 in a Cell-Free Kinase Activity Assay.The maximum activation of PDK1 compared to DMSO control of (R)-PS210 is 5.5 fold.
Chemical Properties
Molecular Weight380.31
FormulaC19H15F3O5
Cas No.1410101-89-1
Relative Density.1.400 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

PS-210PS210PS 210PDK1AC50(R)-PS-210(R)PS210(R) PS210
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