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(R)-Q-VD-OPh

Catalog No. T13445

(R)-Q-VD-OPh is the less active enantiomer of Q-VD-OPha. Q-VD-OPha is an irreversible inhibitor of pan-caspase, with potent antiapoptotic properties.

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Product Introduction

Bioactivity

Description	(R)-Q-VD-OPh is the less active enantiomer of Q-VD-OPha. Q-VD-OPha is an irreversible inhibitor of pan-caspase, with potent antiapoptotic properties.
Alias	(R)-Quinoline-Val-Asp-Difluorophenoxymethylketone, (R)-QVD-OPH

Chemical Properties

Molecular Weight	513.49
Formula	C26H25F2N3O6
Cas No.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 125 mg/mL (243.43 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9475 mL	9.7373 mL	19.4746 mL	97.3729 mL
5 mM	0.3895 mL	1.9475 mL	3.8949 mL	19.4746 mL
10 mM	0.1947 mL	0.9737 mL	1.9475 mL	9.7373 mL
20 mM	0.0974 mL	0.4869 mL	0.9737 mL	4.8686 mL
50 mM	0.0389 mL	0.1947 mL	0.3895 mL	1.9475 mL
100 mM	0.0195 mL	0.0974 mL	0.1947 mL	0.9737 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Q-VD-OPh(R)QVDOPh(R) Q VD OPhQVD-OPHQuinoline-Val-Asp-Difluorophenoxymethylketone