Popular Searches
MCC950 sodiumDiphenyleneiodonium chlorideMG-132Ferrostatin-1Stattic
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact Us
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TOPBioactivityChemical infoStorage&SolubilityCalculator

(R,S)-Anatabine (tartrate) (2743-90-0 free base)

😃Good
Catalog No. T23228
Alias (R,S)-Anatabine (tartrate)

Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tartrate) is preferable to (R,S)-Anatabine for certain applications and formulations.

(R,S)-Anatabine (tartrate) (2743-90-0 free base)
Other Forms of (R,S)-Anatabine (tartrate) (2743-90-0 free base):

(R,S)-Anatabine (tartrate) (2743-90-0 free base)

😃Good
Catalog No. T23228Alias (R,S)-Anatabine (tartrate)
Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tartrate) is preferable to (R,S)-Anatabine for certain applications and formulations.
Pack SizePriceAvailabilityQuantity
5 mg$98Backorder
10 mg$173Backorder
50 mg$760Backorder
100 mg$1,327Backorder
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tart
In vitro
In vitro: Anatabine dose-dependently lowered Aβ1-40 and Aβ1-42 levels and reduced sAPPβ production without any effects on sAPPα levels. Anatabine lowered Aβ production by mainly impacting the β-cleavage of APP. Anatabine lowered NFκB activation. Anatabine inhibited BACE-1 transcription and reduced BACE-1 protein levels in human neuronal-like SHSY-5Y cells. (R,S)-Anatabine also dose-dependently inhibits NF-κB activation [1].
In vivo
In vivo: In a transgenic mouse model with AD, treatment with anatabine for 4 days remarkably lowered brain soluble Aβ1-40 and Aβ1-42 levels [1].
Alias(R,S)-Anatabine (tartrate)
Chemical Properties
Molecular Weight310.3
FormulaC10H12O2·C4H6O6
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/mL
Ethanol: ≤1 mg/mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

2743-90-0 free base(R,S)Anatabine (tartrate) (2743900 free base)Anatabine (tartrate)Anatabine2743-90-0(R,S) Anatabine (tartrate) (2743 90 0 free base)
Related Tags: buy (R,S)-Anatabine (tartrate) (2743-90-0 free base) | purchase (R,S)-Anatabine (tartrate) (2743-90-0 free base) | (R,S)-Anatabine (tartrate) (2743-90-0 free base) cost | order (R,S)-Anatabine (tartrate) (2743-90-0 free base) | (R,S)-Anatabine (tartrate) (2743-90-0 free base) chemical structure | (R,S)-Anatabine (tartrate) (2743-90-0 free base) in vivo | (R,S)-Anatabine (tartrate) (2743-90-0 free base) in vitro | (R,S)-Anatabine (tartrate) (2743-90-0 free base) formula | (R,S)-Anatabine (tartrate) (2743-90-0 free base) molecular weight
TargetMol | Logo

Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.