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(Rac)-BL-918

Name: (Rac)-BL-918
Brand: TargetMol
SKU: T12662
Rating: 4.5 (1 reviews)

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Catalog No. T12662Cas No. 2435589-07-2

(Rac)-BL-918 is the racemate of BL-918, a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM, inducing cytoprotective autophagy for Parkinson’s disease treatment [1].

(Rac)-BL-918

😃Good

Catalog No. T12662Cas No. 2435589-07-2

(Rac)-BL-918 is the racemate of BL-918, a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM, inducing cytoprotective autophagy for Parkinson’s disease treatment [1].

Pack Size	Price	Availability	Quantity
200 mg	$1,187	6-8 weeks

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Product Introduction

Bioactivity

Description

(Rac)-BL-918 is the racemate of BL-918, a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM, inducing cytoprotective autophagy for Parkinson’s disease treatment [1].

Chemical Properties

Molecular Weight	533.44
Formula	C₂₃H₁₅F₈N₃OS
Cas No.	2435589-07-2
Relative Density.	1.508 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 125 mg/mL (234.33 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8746 mL	9.3731 mL	18.7463 mL	93.7313 mL
5 mM	0.3749 mL	1.8746 mL	3.7493 mL	18.7463 mL
10 mM	0.1875 mL	0.9373 mL	1.8746 mL	9.3731 mL
20 mM	0.0937 mL	0.4687 mL	0.9373 mL	4.6866 mL
50 mM	0.0375 mL	0.1875 mL	0.3749 mL	1.8746 mL
100 mM	0.0187 mL	0.0937 mL	0.1875 mL	0.9373 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

BL-918(Rac) BL 918BL 918(Rac)BL918BL918