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(S)-KT109

Name: (S)-KT109
Brand: TargetMol
SKU: T38148
Rating: 4.5 (1 reviews)

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Catalog No. T38148Cas No. 2055172-61-5

Alias (S)-KT109

(S)-KT109 is the (S) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (S)-KT109 is a less potent inhibitor of DAGLβ (IC50 = 39.81 nM), DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (IC50 = 794.3 nM), and α/β-hydrolase domain-containing protein 6 (ABHD6; IC50 = 630.9 nM) than (R)-KT109 .

(S)-KT109

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Catalog No. T38148Alias (S)-KT109Cas No. 2055172-61-5

Pack Size	Price	Availability	Quantity
500 μg	$233	35 days
1 mg	$440	35 days

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Product Introduction

Bioactivity

Description	(S)-KT109 is the (S) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (S)-KT109 is a less potent inhibitor of DAGLβ (IC50 = 39.81 nM), DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (IC50 = 794.3 nM), and α/β-hydrolase domain-containing protein 6 (ABHD6; IC50 = 630.9 nM) than (R)-KT109 .
Alias	(S)-KT109

Chemical Properties

Molecular Weight	422.52
Formula	C₂₇H₂₆N₄O
Cas No.	2055172-61-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMF: 10 mg/mL (23.67 mM), Sonication is recommended.

DMSO: 10 mg/mL (23.67 mM), Sonication is recommended.

Solution Preparation Table

DMF/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3668 mL	11.8338 mL	23.6675 mL	118.3376 mL
5 mM	0.4734 mL	2.3668 mL	4.7335 mL	23.6675 mL
10 mM	0.2367 mL	1.1834 mL	2.3668 mL	11.8338 mL
20 mM	0.1183 mL	0.5917 mL	1.1834 mL	5.9169 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

KT109KT 109KT-109(S)KT109(S) KT109(S)-KT-109