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(S)-Lisofylline

Name: (S)-Lisofylline
Brand: TargetMol
SKU: T22148
Price: -1 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22148Cas No. 100324-80-9

(S)-Lisofylline is the inactive optical enantiomer of (R)-lisofylline which is an anti-inflammatory agent. (S)-Lisofylline is exclusively converted to pentoxifylline in human liver microsomes.

(S)-Lisofylline

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Purity: 99.61%

Catalog No. T22148Cas No. 100324-80-9

(S)-Lisofylline is the inactive optical enantiomer of (R)-lisofylline which is an anti-inflammatory agent. (S)-Lisofylline is exclusively converted to pentoxifylline in human liver microsomes.

Pack Size	Price	Availability
1 mg	$87	In Stock
5 mg	Inquiry	In Stock
50 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	$312	In Stock

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Purity:99.61%

Resource Download

COA HNMR HPLC

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Product Introduction

Bioactivity

Description

(S)-Lisofylline is the inactive optical enantiomer of (R)-lisofylline which is an anti-inflammatory agent. (S)-Lisofylline is exclusively converted to pentoxifylline in human liver microsomes.

Chemical Properties

Molecular Weight	280.32
Formula	C₁₃H₂₀N₄O₃
Cas No.	100324-80-9
Smiles	C[C@H](O)CCCCn1c(=O)n(C)c2ncn(C)c2c1=O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (178.36 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5674 mL	17.8368 mL	35.6735 mL	178.3676 mL
5 mM	0.7135 mL	3.5674 mL	7.1347 mL	35.6735 mL
10 mM	0.3567 mL	1.7837 mL	3.5674 mL	17.8368 mL
20 mM	0.1784 mL	0.8918 mL	1.7837 mL	8.9184 mL
50 mM	0.0713 mL	0.3567 mL	0.7135 mL	3.5674 mL
100 mM	0.0357 mL	0.1784 mL	0.3567 mL	1.7837 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Lisofylline(S)Lisofylline(S) Lisofylline