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(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $170 | 35 days | |
1 mg | $325 | 35 days | |
5 mg | $1,330 | 35 days | |
10 mg | $2,340 | 35 days |
Description | (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononuclear cells (IC50s = 0.37 and 0.044 μM, respectively). |
Alias | (S)-p38 MAPK Inhibitor III |
Molecular Weight | 404.5 |
Formula | C23H21FN4S |
Cas No. | 581098-48-8 |
Relative Density. | 1.30 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: 12 mg/mL Ethanol: 30 mg/mL Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/mL DMF: 20 mg/mL |
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