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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,400 | 6-8 weeks | |
50 mg | $1,820 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | (S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα, with an IC50 of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ, PI3Kδ, and PI3Kγ, respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer[1]. (S)-PI3Kα-IN-4 (compound 11) is a quinazolin-4(3H)-one derivative with 2-substituted-N-methylpropanamide substitution[1]. [1]. Dong J, et, al. Discovery of 3-Quinazolin-4(3 H)-on-3-yl-2, N-dimethylpropanamides as Orally Active and Selective PI3Kα Inhibitors. ACS Med Chem Lett. 2020 Jun 10;11(7):1463-1469. |
Alias | (S)-PI3Kα-IN-4 |
Molecular Weight | 560 |
Formula | C25H23ClFN5O5S |
Cas No. | 2322293-84-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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