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(VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH), also known as (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a conjugate compound comprising a ligand-linker that targets E3 ligase and features a VHL ligand on one end. It is employed in PROTAC technology applications.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $531 | Backorder | |
25 mg | $995 | Backorder | |
50 mg | Inquiry | Backorder | |
100 mg | Inquiry | Backorder |
Description | (VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH), also known as (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a conjugate compound comprising a ligand-linker that targets E3 ligase and features a VHL ligand on one end. It is employed in PROTAC technology applications. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the specific protein. By harnessing the intracellular ubiquitin-proteasome system, PROTACs achieve selective degradation of target proteins [2]. |
Alias | VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH |
Molecular Weight | 754.99 |
Formula | C39H58N6O7S |
Cas No. | 2086301-47-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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