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(S,R,S)-AHPC-Me-C5-COOH

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Catalog No. T18670Cas No. 2229976-21-8

(S,R,S)-AHPC-Me-C5-COOH is a synthetic E3 ligase ligand-linker conjugate composed of a VHL ligand and a linker, used in PROTAC DT2216[1].

(S,R,S)-AHPC-Me-C5-COOH

(S,R,S)-AHPC-Me-C5-COOH

😃Good
Catalog No. T18670Cas No. 2229976-21-8
(S,R,S)-AHPC-Me-C5-COOH is a synthetic E3 ligase ligand-linker conjugate composed of a VHL ligand and a linker, used in PROTAC DT2216[1].
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100 mgInquiry7-10 days
500 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
(S,R,S)-AHPC-Me-C5-COOH is a synthetic E3 ligase ligand-linker conjugate composed of a VHL ligand and a linker, used in PROTAC DT2216[1].
In vitro
DT2216 is a selective degrader of B-cell lymphoma extra large (BCL-XL) via PROTAC technology[1].
Chemical Properties
Molecular Weight586.74
FormulaC30H42N4O6S
Cas No.2229976-21-8
Relative Density.1.240 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

(S,R,S) AHPC Me C5 COOHAHPC-Me-C5-COOH(S,R,S)AHPCMeC5COOH(S,R,S)-AHPC-Me-C-5-COOH
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