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(S,R,S)-AHPC-PEG5-COOH

Name: (S,R,S)-AHPC-PEG5-COOH
Brand: TargetMol
SKU: T18872
Price: 34 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T18872Cas No. 2172820-14-1

Alias VHL Ligand-Linker Conjugates 16, VH032-PEG5-COOH, E3 Ligase Ligand-Linker Conjugates 58

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for PROTAC technology, comprising the (S,R,S)-AHPC-based VHL ligand and a 5-unit PEG linker [1].

(S,R,S)-AHPC-PEG5-COOH

😃Good

Catalog No. T18872Alias VHL Ligand-Linker Conjugates 16, VH032-PEG5-COOH, E3 Ligase Ligand-Linker Conjugates 58Cas No. 2172820-14-1

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for PROTAC technology, comprising the (S,R,S)-AHPC-based VHL ligand and a 5-unit PEG linker [1].

Pack Size	Price	Availability	Quantity
2 mg	$46	5 days

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Product Introduction

Bioactivity

Description	(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for PROTAC technology, comprising the (S,R,S)-AHPC-based VHL ligand and a 5-unit PEG linker [1].
Alias	VHL Ligand-Linker Conjugates 16, VH032-PEG5-COOH, E3 Ligase Ligand-Linker Conjugates 58

Chemical Properties

Molecular Weight	750.9
Formula	C₃₆H₅₄N₄O₁₁S
Cas No.	2172820-14-1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (133.17 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3317 mL	6.6587 mL	13.3174 mL	66.5868 mL
5 mM	0.2663 mL	1.3317 mL	2.6635 mL	13.3174 mL
10 mM	0.1332 mL	0.6659 mL	1.3317 mL	6.6587 mL
20 mM	0.0666 mL	0.3329 mL	0.6659 mL	3.3293 mL
50 mM	0.0266 mL	0.1332 mL	0.2663 mL	1.3317 mL
100 mM	0.0133 mL	0.0666 mL	0.1332 mL	0.6659 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

(S,R,S) AHPC PEG5 COOH(S,R,S)AHPCPEG5COOHAHPC-PEG5-COOH(S,R,S)-AHPC-PEG-5-COOH