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(S,R,S)-AHPC-propargyl

Catalog No. T13876Cas No. 2098799-78-9

(S,R,S)-AHPC-propargyl is a VHL ligand which is used in "click reaction" for PROTACs.

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Pack Size	Price	Availability	Quantity
2 mg	$83	5 days

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Product Introduction

Bioactivity

Description	(S,R,S)-AHPC-propargyl is a VHL ligand which is used in "click reaction" for PROTACs.
Alias	VHL ligand 7, VH032-propargyl

Chemical Properties

Molecular Weight	526.65
Formula	C27H34N4O5S
Cas No.	2098799-78-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (189.88 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8988 mL	9.4940 mL	18.9879 mL	94.9397 mL
5 mM	0.3798 mL	1.8988 mL	3.7976 mL	18.9879 mL
10 mM	0.1899 mL	0.9494 mL	1.8988 mL	9.4940 mL
20 mM	0.0949 mL	0.4747 mL	0.9494 mL	4.7470 mL
50 mM	0.0380 mL	0.1899 mL	0.3798 mL	1.8988 mL
100 mM	0.0190 mL	0.0949 mL	0.1899 mL	0.9494 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc