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(S,S)-BMS-984923

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Catalog No. T74185Cas No. 1375752-77-4

(S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923, exhibiting an EC50 >1μM for the mGluR5 receptor [1]. BMS-984923, in contrast, is a potent mGluR5 silent allosteric modulator [2].

(S,S)-BMS-984923
Other Forms of (S,S)-BMS-984923:
BMS-984923T387891375752-78-5
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(S,S)-BMS-984923

😃Good
Catalog No. T74185Cas No. 1375752-77-4
(S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923, exhibiting an EC50 >1μM for the mGluR5 receptor [1]. BMS-984923, in contrast, is a potent mGluR5 silent allosteric modulator [2].
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Product Introduction

Bioactivity
Description
(S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923, exhibiting an EC50 >1μM for the mGluR5 receptor [1]. BMS-984923, in contrast, is a potent mGluR5 silent allosteric modulator [2].
Chemical Properties
Molecular Weight374.82
FormulaC22H15ClN2O2
Cas No.1375752-77-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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