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α-GalCer analog 8

Catalog No. T35450Cas No. 922727-14-8

α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 µg per animal dose, indicating a Th2 response.

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Pack Size	Price	Availability	Quantity
500 μg	$592	35 days

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Product Introduction

Bioactivity

Description

Alias

α-GalCer analog 8, α-Galactosylceramide analog 8

Chemical Properties

Molecular Weight	868.339
Formula	C50H97N3O8
Cas No.	922727-14-8

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility Information	Ethanol: Soluble Methanol: Soluble DMSO: Soluble DMF: Soluble

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

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