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β-Bisabolene
β-Bisabolene, a sesquiterpene extracted from Opoponax (Commiphora guidotti), serves as an anticancer agent with potential applications in breast cancer research.
Catalog No. T40578Cas No. 495-61-4
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β-Bisabolene
Catalog No. T40578Cas No. 495-61-4
β-Bisabolene, a sesquiterpene extracted from Opoponax (Commiphora guidotti), serves as an anticancer agent with potential applications in breast cancer research.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | Inquiry | 7-10 days | |
| 100 mg | Inquiry | 7-10 days |
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Bioactivity
Chemical Properties
| Description | β-Bisabolene, a sesquiterpene extracted from Opoponax (Commiphora guidotti), serves as an anticancer agent with potential applications in breast cancer research. |
| In vitro | β‐bisabolene exhibits selective cytotoxic activity for mouse cells, it against normal Eph4, MG1361 and 4T1 cells with IC 50 values of >200?μg/ml, 65.49?μg/ml, and 48.99?μg/ml, respectively. It against normal MCF‐10A, MCF‐7, MDA‐MB‐231, SKBR3 and BT474 cells with IC 50 values of 114.3?μg/ml, 66.91?μg/ml, 98.39?μg/ml, 70.62?μg/ml and 74.3?μg/ml, respectively[1]. |
| In vivo | β‐bisabolene is effective in reducing the growth of transplanted 4T1 mammary tumours?in vivo?(37.5% reduction in volume by endpoint)[1]. |
| Molecular Weight | 204.35 |
| Formula | C15H24 |
| Cas No. | 495-61-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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