Shopping Cart
- Remove All
Your shopping cart is currently empty
(+)-Intermedine
😃Good
Catalog No. T38429Cas No. 10285-06-0
(+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxic activity against neural progenitor cells (NPCs).
(+)-Intermedine
😃Good
Catalog No. T38429Cas No. 10285-06-0
(+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxic activity against neural progenitor cells (NPCs).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | (+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxic activity against neural progenitor cells (NPCs). |
| In vitro | '(+)-Intermedine, at concentrations ranging from 1.1 to 30 μM over 24 hours, demonstrates considerable cytotoxic effects at 30 μM, significantly diminishing cell viability in a dose-dependent fashion in neural progenitor cells (NPCs)[1]. It does not impair differentiation[1]. In a Cell Cytotoxicity Assay on NPCs, with concentrations set at 1.1, 3.3, 10, and 30 μM for an incubation period of 24 hours, the results confirmed significant cytotoxicity and reduced viability at the highest concentration.' |
| Molecular Weight | 299.36 |
| Formula | C15H25NO5 |
| Cas No. | 10285-06-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy (+)-Intermedine | purchase (+)-Intermedine | (+)-Intermedine cost | order (+)-Intermedine | (+)-Intermedine chemical structure | (+)-Intermedine in vitro | (+)-Intermedine formula | (+)-Intermedine molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.