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(1S,2S,3R)-DT-061

Catalog No. T10060Cas No. 1809427-20-0

(1S,2S,3R)-DT-061 is an enantiomer of DT-061 which is an orally bioavailable activator of PP2A.

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Pack Size	Price	Availability
25 mg	$1,230	6-8 weeks
50 mg	$1,610	6-8 weeks
100 mg	$2,500	6-8 weeks

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Product Introduction

Bioactivity

Description

(1S,2S,3R)-DT-061 is an enantiomer of DT-061 which is an orally bioavailable activator of PP2A.

Chemical Properties

Molecular Weight	520.52
Formula	C25H23F3N2O5S
Cas No.	1809427-20-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 125 mg/mL (240.14 mM)

MEthanol: 25 mg/mL (48.03 mM)

Solution Preparation Table

DMSO/MEthanol

	1mg	5mg	10mg	50mg
1 mM	1.9212 mL	9.6058 mL	19.2116 mL	96.0578 mL
5 mM	0.3842 mL	1.9212 mL	3.8423 mL	19.2116 mL
10 mM	0.1921 mL	0.9606 mL	1.9212 mL	9.6058 mL
20 mM	0.0961 mL	0.4803 mL	0.9606 mL	4.8029 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0384 mL	0.1921 mL	0.3842 mL	1.9212 mL
100 mM	0.0192 mL	0.0961 mL	0.1921 mL	0.9606 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc