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(2-Hydroxyethoxy)acetic acid
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Catalog No. T38735Cas No. 13382-47-3
Alias β-hydroxyethoxyacetic acid, HEAA
(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the primary urinary metabolite of 1,4-dioxane, serving as a reliable and sensitive short-term biomarker in urine.
(2-Hydroxyethoxy)acetic acid
😃Good
Catalog No. T38735Alias β-hydroxyethoxyacetic acid, HEAACas No. 13382-47-3
(2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the primary urinary metabolite of 1,4-dioxane, serving as a reliable and sensitive short-term biomarker in urine.
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| 500 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the primary urinary metabolite of 1,4-dioxane, serving as a reliable and sensitive short-term biomarker in urine. |
| In vitro | (2-Hydroxyethoxy)acetic acid (HEAA) exhibits a pH-dependent equilibrium with its cyclic lactone form, dioxan-2-one, maintaining a stable open-chain structure in acidic conditions[1]. |
| In vivo | The primary metabolic route for 1,4-Dioxane involves its oxidation by cytochrome P450 monooxygenase into (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA), which is subsequently rapidly eliminated through urinary excretion[1]. |
| Alias | β-hydroxyethoxyacetic acid, HEAA |
| Molecular Weight | 120.1 |
| Formula | C4H8O4 |
| Cas No. | 13382-47-3 |
| Relative Density. | 1.290 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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