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Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | 1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a polyethylene glycol (PEG)-based linker compound suitable for the synthesis of proteolysis-targeting chimeras (PROTACs) [1]. |
In vitro | PROTACs, comprising two ligands connected by a linker, utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins; one ligand binds an E3 ubiquitin ligase, and the other binds the target protein [1]. |
Alias | 1-3-bis-carboxyethoxy-2-2-bis-carboxyethoxy-propane |
Molecular Weight | 424.4 |
Formula | C17H28O12 |
Cas No. | 35638-19-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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