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1,7-Bis-Boc-1,4,7-triazaheptane

Name: 1,7-Bis-Boc-1,4,7-triazaheptane
Brand: TargetMol
SKU: T13991
Rating: 4.5 (1 reviews)

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Catalog No. T13991Cas No. 117499-16-8

1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker used for synthesizing PROTACs [1].

1,7-Bis-Boc-1,4,7-triazaheptane

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Catalog No. T13991Cas No. 117499-16-8

1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker used for synthesizing PROTACs [1].

Pack Size	Price	Availability	Quantity
100 mg	Inquiry	7-10 days
500 mg	Inquiry	7-10 days

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Product Introduction

Bioactivity

Description	1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker used for synthesizing PROTACs [1].
In vitro	PROTACs comprise two distinct ligands linked by a connector: one ligand binds to an E3 ubiquitin ligase, while the other targets the specific protein. By utilizing the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1].

Chemical Properties

Molecular Weight	303.4
Formula	C₁₄H₂₉N₃O₄
Cas No.	117499-16-8
Relative Density.	1.035 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Keywords

Alkyl/ether1,7-Bis-Boc-1,4,7-triazaheptane1,7BisBoc1,4,7triazaheptane1,7 Bis Boc 1,4,7 triazaheptane

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