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1-Methyl-4-imidazoleacetic Acid (hydrochloride)

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Catalog No. T37279Cas No. 35454-39-8

1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.

1-Methyl-4-imidazoleacetic Acid (hydrochloride)

1-Methyl-4-imidazoleacetic Acid (hydrochloride)

😃Good
Catalog No. T37279Cas No. 35454-39-8
1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.
Pack SizePriceAvailabilityQuantity
10 mg$98 35 days
50 mg$458 35 days
100 mg$788 35 days
250 mg$1,750 35 days
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Product Introduction

Bioactivity
Description
1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.
Chemical Properties
Molecular Weight176.601
FormulaC6H9ClN2O2
Cas No.35454-39-8
Relative Density.1.27g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 2 mg/mL (11.32 mM), Sonication is recommended.
DMF: 2 mg/mL (11.32 mM), Sonication is recommended.
PBS (pH 7.2): 10 mg/mL (56.62 mM), Sonication is recommended.
DMSO: 10 mg/mL (56.62 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMF/PBS (pH 7.2)/DMSO
1mg5mg10mg50mg
1 mM5.6625 mL28.3124 mL56.6248 mL283.1241 mL
5 mM1.1325 mL5.6625 mL11.3250 mL56.6248 mL
10 mM0.5662 mL2.8312 mL5.6625 mL28.3124 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

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