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14-Anhydrodigitoxigenin

Name: 14-Anhydrodigitoxigenin
Brand: TargetMol
SKU: T37707
Rating: 4.5 (1 reviews)

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Catalog No. T37707Cas No. 4321-20-4

14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 μM.2

14-Anhydrodigitoxigenin

😃Good

Catalog No. T37707Cas No. 4321-20-4

14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 μM.2

Pack Size	Price	Availability
5 mg	$143	35 days
10 mg	$268	35 days
25 mg	$550	35 days
50 mg	$987	35 days

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Product Introduction

Bioactivity

Description

14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 μM.2

Chemical Properties

Molecular Weight	356.506
Formula	C₂₃H₃₂O₃
Cas No.	4321-20-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMF:PBS (pH 7.2) (1:1): 0.5 mg/mL (1.4 mM), Sonication is recommended.

DMSO: 20 mg/mL (56.1 mM), Sonication is recommended.

DMF: 25 mg/mL (70.13 mM), Sonication is recommended.

Ethanol: 5 mg/mL (14.03 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.5610 mL	2.8050 mL	5.6100 mL	28.0500 mL
10 mM	0.2805 mL	1.4025 mL	2.8050 mL	14.0250 mL

DMSO/DMF

	1mg	5mg	10mg	50mg
20 mM	0.1403 mL	0.7013 mL	1.4025 mL	7.0125 mL
50 mM	0.0561 mL	0.2805 mL	0.5610 mL	2.8050 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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