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16-Keto Aspergillimide

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Catalog No. T38235Cas No. 199784-50-4

16-Keto Aspergillimide (SB202327) is a novel anthelmintic compound derived from the Aspergillus strain [IMI 337664].

16-Keto Aspergillimide

16-Keto Aspergillimide

😃Good
Catalog No. T38235Cas No. 199784-50-4
16-Keto Aspergillimide (SB202327) is a novel anthelmintic compound derived from the Aspergillus strain [IMI 337664].
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Product Introduction

Bioactivity
Description
16-Keto Aspergillimide (SB202327) is a novel anthelmintic compound derived from the Aspergillus strain [IMI 337664].
In vitro
The oral efficacy of 16-Keto Aspergillimide (SB202327) against adult Trichostrongylus colubriformis infections in gerbils was evaluated. Bioassay-guided extraction utilizing Haemonchus contortus L3 larvae demonstrated that 16-Keto Aspergillimide (SB202327) exhibits activity in vitro, however, it did not show effectiveness in vivo[1].
Chemical Properties
Molecular Weight373.453
FormulaC20H27N3O4
Cas No.199784-50-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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