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19 alpha-Hydroxyasiatic acid shows significant anticoagulant effect on the extrinsic pathway.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $337 | 5 days |
Description | 19 alpha-Hydroxyasiatic acid shows significant anticoagulant effect on the extrinsic pathway. |
In vitro | Phytochemical examination of the ethyl acetate extract of the fruit yielded eight compounds of the 19-α±-hydroxyursane type: euscaphic acid (1), 1-β-hydroxyeuscaphic acid (2), hyptatic acid B (3), 19 alpha-Hydroxyasiatic acid(4), trachelosperogenin (5), 4-epi-nigaichigoside F1 (6), nigaichigoside F1 (7), and trachelosperoside B-1 (8), as confirmed by NMR spectroscopy. Inhibition of cell proliferation by these compounds were determined by using MCF-7 (breast), SF-268 (CNS), NCI H460 (lung), HCT-116 (colon) and AGS (gastric) human tumour cells. Among the human tumour cell lines assayed, only compounds 3 and 6 displayed significant growth inhibition and was specific to colon tumour cells by 56% and 40%, respectively. These ursolic acid analogues were also tested for anti-inflammatory activity using in vitro cycloxegenase-1 (COX-1) and cycloxegenase-2 (COX-2) enzyme inhibitory assays[1] |
Alias | 19 alpha-Hydroxyasiatic acid |
Molecular Weight | 504.708 |
Formula | C30H48O6 |
Cas No. | 70868-78-9 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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