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2,3-dihydroxy-3-methylbutanoic acid

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Catalog No. T50050Cas No. 1756-18-9

2,3-dihydroxy-3-methylbutanoic acid is a natural metabolite of the branched-chain amino acid leucine. It acts by activating the mTOR signaling pathway to promote the synthesis of new muscle proteins and reduce the breakdown of existing proteins, thereby increasing muscle mass and improving recovery from exercise.

2,3-dihydroxy-3-methylbutanoic acid

2,3-dihydroxy-3-methylbutanoic acid

🥰Excellent
Purity: 99.03%
Catalog No. T50050Cas No. 1756-18-9
2,3-dihydroxy-3-methylbutanoic acid is a natural metabolite of the branched-chain amino acid leucine. It acts by activating the mTOR signaling pathway to promote the synthesis of new muscle proteins and reduce the breakdown of existing proteins, thereby increasing muscle mass and improving recovery from exercise.
Pack SizePriceAvailabilityQuantity
1 mg$55In Stock
2 mg$83In Stock
5 mg$128In Stock
10 mg$192In Stock
25 mg$328In Stock
50 mg$491In Stock
100 mg$716In Stock
500 mg$1,480In Stock
1 mL x 10 mM (in DMSO)$97In Stock
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Purity:99.03%
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Product Introduction

Bioactivity
Description
2,3-dihydroxy-3-methylbutanoic acid is a natural metabolite of the branched-chain amino acid leucine. It acts by activating the mTOR signaling pathway to promote the synthesis of new muscle proteins and reduce the breakdown of existing proteins, thereby increasing muscle mass and improving recovery from exercise.
Chemical Properties
Molecular Weight134.1305
FormulaC5H10O4
Cas No.1756-18-9
SmilesCC(C)(O)C(O)C(O)=O
Relative Density.1.326g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (410.05 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.4554 mL37.2771 mL74.5543 mL372.7713 mL
5 mM1.4911 mL7.4554 mL14.9109 mL74.5543 mL
10 mM0.7455 mL3.7277 mL7.4554 mL37.2771 mL
20 mM0.3728 mL1.8639 mL3.7277 mL18.6386 mL
50 mM0.1491 mL0.7455 mL1.4911 mL7.4554 mL
100 mM0.0746 mL0.3728 mL0.7455 mL3.7277 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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